A 12 year old adolescent presented with refractory seizures and was Spreaders found to have a mesial temporal lobe lesion.The patient underwent biopsy and was diagnosed with an arteriorvenous malformation.Supratentorial lesions in the pediatric population can have a large variety of underlying etiologies and it can challenging to differentiate on n
Development of disease-modifying therapies including monoclonal antibody (mAb)-based therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over the past decades.Most of the mAb-based therapies approved for MS deplete immune cell subsets and act through activation of cellular Fc-gamma receptors expressed by cytotoxi
The radical change of politics and ideology in the post-Communist states in the Yugoslav area caused a revaluation of national histories.The production of desirable history has the political support of the current authorities in the states that emerged from the break-up of Yugoslavia.The features of revaluing the past and writing desirable history
Perforin-2 (P2) is a pore-forming protein with cytotoxic activity against intracellular bacterial pathogens.P2 knockout (P2KO) mice are unable to control infections and die from normally non-lethal bacterial infections.Here we show that P2KO mice as compared to WT mice show significantly higher levels of systemic inflammation, measured by inflammat